ABSTRACT
La alogenosis iatrogénica es la enfermedad causada por la aplicación de biopolímeros con fines estéticos. Sus manifestaciones clínicas pueden presentarse entre las seis horas y los 30 años posteriores a la aplicación, con síntomas locales o sistémicos. El principal rasgo de la histopatología es la presencia de granulomas por cuerpo extraño con reacción de tipo sarcoideo, la cual es difícil de Interpretar por su asociación con la sarcoidosis. Se reporta aquí el caso de una paciente con lesiones granulomatosas de tipo sarcoideo por reacción a cuerpo extraño, secundaria a la aplicación de múltiples sustancias desconocidas en cara y glúteos.
Iatrogenic allogenosis is a disease caused by the injection of biopolymers with esthetic purposes. Clinical manifestations can occur between six hours and 30 years after the procedure with local and/or systemic symptoms. The pathological findings are characterized by the presence of foreign body granulomas with a sarcoid-like reaction. Its Interpretation Is difficult given Its association with sarcoidosis. We report the clinical case of a female patient with granulomatous lesions In reaction to a foreign body secondary to the multiple application of unknown substances on the face and buttocks.
Subject(s)
Biopolymers , Sarcoidosis , Granuloma, Foreign-BodyABSTRACT
La fractura de instrumental rotatorio es una complicación transoperatoria rara en cirugía de terceros molares, cuando pasa desapercibida, su diagnóstico como cuerpo extraño suele ser un hallazgo radiográfico y su extracción requiere una valoración minuciosa. Se presenta el caso clínico de un paciente femenino de 21 años, que acude al servicio de Cirugía de la Facultad de Odontología de la Universidad Central del Ecuador (FOUCE), referida por el hallazgo radiográfico de un cuerpo extraño en la mandíbula posterior izquierda, en la historia refiere la extracción de terceros molares inferiores hace 5 años; sin signos clínicos al examen intrao-ral, en el estudio radiográfico se observó la presencia de una sombra radiopaca en la parte distal del órgano dental #37, se confirma en la tomografía como imagen compatible con una fresa fraccionada entre la parte activa y pasiva. El diagnóstico fue alojamiento intraóseo de cuerpo extraño dividido en 2 fragmentos. El trata-miento consistió en la exéresis de la parte pasiva de la fresa, se decidió no extraer la parte activa localizada debajo del paquete vasculonervioso, por riesgo de lesión del nervio dentario inferior. En el posoperatorio se realizaron controles clínicos, radiográficos y tomográficos, no se evidenciaron complicaciones, la paciente se ha mantenido asintomática y estable.
Rotating instrument fracture is a rare trans-operation complication in third molar surgery. When it goes un-noticed, its diagnosis as a foreign body is usually a radiographic finding and its extraction requires careful evaluation. A clinical case of a 21-year-old female patient is presented, who comes to the Surgery service of the Faculty of Dentistry of the Central University of Ecuador (FOUCE), referred by the radiographic finding of a foreign body in the left posterior jaw, the history refers to the extraction of lower third molars 5 years ago; without clinical signs on intraoral examination, in the radiographic study the presence of a radiopaque shadow was observed in the distal part of dental organ # 37, confirmed on tomography as an image compatible with a fractional drill between the active and passive parts. The diagnosis was of an intra-osseous foreign body placed and divided into 2 fragments. The treatment consisted of the excision of the passive part of the drill; it was decided not to extract the active part located below the nervous-vascular package, due to the risk of injury to the lower dental nerve. In the post-operation period, clinical, radiographic and tomographic controls were performed, no complications were observed, the patient remained asymptomatic and stable.
A fratura de instrumental rotatório é uma complicação transoperatória rara na cirurgia de terceiros molares, quando passar despercebida, seu diagnóstico como corpo estranho pode ser um achado radiográfico e sua extração requer avaliação cuidadosa. Apresentamos um caso clínico de uma paciente do sexo feminino, 21 anos, atendida no serviço de Cirurgia da Faculdade de Odontologia da Universidade Central do Equador (FOUCE), foi referida pelo achado radiográfico de um corpo estranho na mandíbula posterior esquerda, na história se refere à extração de terceiros molares inferiores há 5 anos; sem sinais clínicos no exame intraoral, o estudo radiográfico mostrou a presença de sombra radiopaca na parte distal do órgão dentário 37, con-firmada na tomografia como imagem compatível com uma broca fracionada entre as partes ativa e passiva. O diagnóstico foi de corpo estranho intraósseo dividido em 2 fragmentos. O tratamento consistiu na excisão da parte passiva da broca, optou-se por não extrair a parte ativa localizada abaixo do feixe vasculonervoso, devido ao risco de lesão do nervo dentário inferior. No pós-operatório, foram realizados controles clínicos, radiográficos e tomográficos, sem complicações, o paciente permaneceu assintomático e estável.Palavras-chave: Terceiro molar, complicações intraoperatórias, complicações pós-operatórias, diagnósti-co por imagem, tomografia, cirurgia oral.
Subject(s)
Surgery, Oral , Diagnostic Imaging , Molar, Third , Postoperative Complications , Granuloma, Foreign-Body , Intraoperative ComplicationsABSTRACT
RESUMEN Paciente de 29 años con antecedente de tres rinomodelaciones en la punta nasal con ácido hialurónico hace cinco años, evaluada por deseo de mejora estética nasal y obstrucción nasal. Al examen visual se observó una leve giba osteocartilaginosa, punta bulbosa, narinas simétricas, sin laterorrinea, no se palparon masas ni nodulaciones. Posterior al manejo de su rinitis y previo consentimiento informado, al realizar rinoseptoplastía abierta se encontró gran cantidad de tejido granulatorio tipo cuerpo extraño en la punta y dorso nasal lo que obligó a cambiar el plan quirúrgico. La biopsia diferida confirmó granuloma por cuerpo extraño por biopolímero derivado de la silicona. Evolucionó satisfactoriamente estética y funcionalmente. La rinomodelación ha aumentado en los últimos años, aunque no existen rellenos faciales aprobados por la FDA para uso nasal. La correcta utilización de los rellenos nasales continúa siendo un tema controvertido. Los granulomas nasales por cuerpo extraño son complicaciones tardías que se han incrementado con el uso de biopolímeros con dosis y técnicas inadecuadas. El uso de ecotomografía ha contribuido a mejorar la planificación quirúrgica, así como el estudio histológico diferido ha permitido identificar el material utilizado en la mayoría de los casos convirtiéndose en el estándar de oro.
ABSTRACT A 29-year-old patient with a history of three nasal fillings in the nasal tip with hyaluronic acid five years ago, reason for consultation improvement nasal aesthetics and nasal obstruction. Physical examination showed a slight osteocartilaginous hump, bulbous tip, symmetrical nostrils, no deviation nasal pyramid, no masses or nodules were palpated. After the management of his rhinitis and previous informed consent, when performing open rhinoseptoplasty, a large amount of foreign body type granulation tissue was found in the tip and nasal dorsum, which forced the surgical plan to change. The post-surgical biopsy showed foreign body granuloma by biopolymer derived from silicone. Evolved satisfactorily aesthetically and functionally. The use of nasal fillers has increased in recent years, although there are no facial fillers approved by the FDA for nasal use. The correct use of nasal fillers is a controversial issue. Nasal granulomas by foreign body are late complications that have increased with the use of biopolymers with inadequate doses and techniques. The use of ecotomography has contributed to improve the surgical planning; the deferred histological study has allowed to identify the material used in most cases becoming the gold standard
Subject(s)
Humans , Female , Adult , Granuloma, Foreign-Body/etiology , Foreign-Body Reaction , Hyaluronic Acid/adverse effects , Silicones , Surgery, Plastic , Biopsy , Nasal Obstruction , Nose/pathology , Foreign BodiesABSTRACT
No abstract available.
Subject(s)
Acupuncture , Foreign Bodies , Granuloma, Foreign-Body , Leprosy , Leprosy, LepromatousABSTRACT
SUMMARY Hypercalcemia associated with silicone-induced granuloma is a rare disease. Diagnosis can be tricky as it is established after ruling out other hypercalcemia-causing entities. In addition, management is customized depending on the patient's wishes and possible solutions. We present a male bodybuilder, in his thirties, with multiple silicone injections in his upper extremities, who developed hypercalcemia and urinary symptoms. Advanced laboratory tests ruled out various causes of hypercalcemia and CT imaging revealed nephrocalcinosis. A biopsy of the upper arm showed granulomatous tissue and inflammation. The patient necessitated two sessions of dialysis and corticosteroids were given to relieve symptoms and reverse laboratory abnormalities. Silicone-induced hypercalcemia should be on high alert because of the increasing trend of body contour enhancements with injections, implants and fillers. Treatment should be optimized depending on the patient's needs and condition.
RESUMO A hipercalcemia associada ao granuloma induzido por silicone é uma doença rara. O diagnóstico pode ser complicado, pois é estabelecido depois de eliminadas outras entidades que causam hipercalcemia. Além disso, o gerenciamento é personalizado, dependendo dos desejos do paciente e das possíveis soluções. Apresentamos um fisiculturista masculino, com trinta e poucos anos, múltiplas injeções de silicone nas extremidades superiores, que desenvolveu hipercalcemia e sintomas urinários. Testes laboratoriais avançados descartaram várias causas de hipercalcemia e a imagem da TC revelou nefrocalcinoses. Uma biópsia da parte superior mostrou tecido granulomatoso e inflamação. O paciente exigiu duas sessões de diálise e foram administrados corticosteroides para aliviar os sintomas e reverter as anormalidades laboratoriais. A hipercalcemia induzida por silicone deve estar em alerta elevado devido à crescente tendência de aprimoramentos do contorno corporal com injeções, implantes e enchimentos. O tratamento deve ser otimizado de acordo com as necessidades e condições do paciente.
Subject(s)
Humans , Male , Adult , Silicones/adverse effects , Granuloma, Foreign-Body/complications , Hypercalcemia/etiology , Weight Lifting , Biopsy , Injections, Intradermal , Granuloma, Foreign-Body/pathology , Hypercalcemia/pathologyABSTRACT
BACKGROUND: The ideal absorbable plating system should provide sufficient rigidity and then be absorbed within a timely manner. The Resorb-X has been recently developed as a plating system with a mixture ratio of 50:50 poly(D, L-lactide). METHODS: We present seven of 121 patients who experienced delayed degradation with this absorbable plate. One hundred twenty-one patients with facial bone fracture underwent surgical treatment from March 2011 to March 2015, and rigid fixation was achieved with the Resorb-X. RESULTS: Of 121 patients, seven (5.8%) developed complications at the surgical sites. Six of 102 cases underwent fixation of the infraorbital rim and one of 73 underwent fixation of the frontozygomatic buttress; the other sites of fixation did not develop delayed degradation. Foreign body granuloma developed at the earliest by postoperative 20 months and at the latest by postoperative 28 months (average, 23.5 months). CONCLUSION: We observed that the use of absorbable plates in incision sites or areas with thin skin can increase the possibility of delayed degradation. When performing surgery in these areas, the normal skin above the fixed location should be covered sufficiently.
Subject(s)
Humans , Bone Plates , Facial Bones , Granuloma, Foreign-Body , Orbital Implants , SkinABSTRACT
OBJECTIVE: The aim of this study was to evaluate the diagnostic value of integrated 18F-fluoro-2-deoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) for suspected recurrence of epithelial ovarian cancer (EOC) with non-disseminated lesions. METHODS: We retrospectively reviewed the medical records of recurrent EOC patients who underwent secondary cytoreduction from January 2000 to December 2013. A total of 134 patients underwent secondary cytoreduction after imaging with either 18F-FDG-PET/CT or contrast-enhanced computed tomography (CECT). RESULTS: In a patient-based analysis of 134 patients, 124 (92.5%) were confirmed to be positive for malignancy. Among 72 patients with suspected non-disseminated recurrence on 18F-FDG-PET/CT, 65 (89.0%) were confirmed to have recurrence, giving 98.5% sensitivity, 87.7% accuracy, and 88.9% positive predictive value (PPV). In the 65 patients with recurrence, residual tumor remained in 14 patients, giving an accuracy of patient selection for secondary cytoreduction of 69.4% (50/72) and it is higher than that of CECT (64.0%). In 169 lesions removed from patients who underwent preoperative 18F-FDG-PET/CT, 135 (79.9%) were confirmed to be positive for malignancy and 124 were accurately detected by 18F-FDG-PET/CT, giving 91.9% sensitivity, 81.1% accuracy, and 85.5% PPV. Foreign body granuloma was found in 33.3% of 21 lesions with false-positive 18F-FDG-PET/CT findings (7/21). The mean preoperative cancer antigen 125 (CA-125) level in false-positive patients was 28.8 U/mL. CONCLUSION: Compared with CECT, 18F-FDG-PET/CT shows higher sensitivity in lesion-based analysis and better accuracy of patient selection for secondary cytoreduction. However, there is still a need for integration of the results of 18F-FDG-PET/CT, CECT, and CA-125 levels to aid treatment planning.
Subject(s)
Humans , Cytoreduction Surgical Procedures , Electrons , Granuloma, Foreign-Body , Medical Records , Neoplasm, Residual , Ovarian Neoplasms , Patient Selection , Recurrence , Retrospective StudiesABSTRACT
Resumen Introducción A pesar de la evidencia sobre los malos resultados y riesgos del uso de inyecciones subcutáneas de silicona para mejorar el contorno corporal, esta técnica sigue siendo utilizada por personas no calificadas. Caso clínico Paciente de 56 años quien consultó por cuadro de celulitis en pierna izquierda. Se obtuvo el antecedente de intervención con silicona en cara, dorso de las manos, glúteos y piernas el año 2000. El cuadro progresó con múltiples abscesos en la totalidad de la pierna y sepsis. Se realizaron aseos quirúrgicos exponiendo planos fascial y muscular, se utilizó terapia local con sistemas de presión negativa y posterior injerto dermo-epidérmico (IDE). El manejo multidisciplinario se realizó en unidades críticas. Los resultados del manejo fueron satisfactorios, salvando la extremidad con cobertura total, logrando el alta luego de 4 meses. Conclusión A pesar de conocerse los peligros de la inyección de silicona, este sigue siendo un procedimiento frecuente. En nuestra paciente se manifestó como fascitis de la pierna, requiriendo tratamiento quirúrgico agresivo. Conocer esta entidad, su diagnóstico y tratamiento es fundamental para tratar pacientes con complicaciones graves.
Introduction Despite the evidence of poor performance and risks of using silicone subcutaneous injections to improve body contour, this technique is still used by untrained people, generating an iatrogenic entity with serious complications. Case report 56 year old female presented left lower extremity cellulitis. A history of previous intervention with silicone injections in face, back of hands, buttocks and legs in year 2000 was obtained. An inflammatory process progressed locally and systemically with multiple abscesses, subcutaneous thickness in the entire leg and sepsis, requiring multiple surgical procedures, reaching fascial and muscle planes exposition of the left leg. The patient underwent local therapy with negative pressure systems and subsequent dermoepidermal graft. Multidisciplinary management was performed on a critical unit. The results were satisfactory, preserving the limb with full coverage. She was discharged after four months of inpatient management. Conclusion Despite knowing the risks of silicone injection (industrial or medical) it remains a common procedure. In our patient she presented as leg fasciitis, requiring aggressive surgical treatment. Knowing this entity, its diagnosis and treatment is essential to treat patients with serious complications.
Subject(s)
Humans , Female , Middle Aged , Silicones/adverse effects , Granuloma, Foreign-Body/surgery , Granuloma, Foreign-Body/chemically induced , Skin Transplantation/methods , Silicones/administration & dosage , Ulcer/chemically induced , Cellulitis/chemically induced , Sepsis , Lower Extremity , Erythema , Fasciitis/chemically induced , Injections, SubcutaneousABSTRACT
Abstract: Pencil core granulomas are still infrequently reported in the literature. A 67-year-old woman presented with a 4mm hard blue subcutaneous nodule on the forehead. She remembered being injured with a pencil tip about 60 years before. The subcutaneous nodule was excised, which microscopically revealed a foreign body reaction with histiocytes containing fragmented coarse black particles. We diagnosed pencil-core granuloma based on the patient's history of pencil tip injury and histological examination findings.
Subject(s)
Humans , Female , Aged , Skin Diseases/pathology , Wounds, Penetrating/complications , Granuloma, Foreign-Body/pathology , Skin Diseases/complications , Granuloma, Foreign-Body/etiology , GraphiteABSTRACT
ABSTRACT We describe the case of a 33-year-old man, a chronic user of powder cocaine, who presented with dyspnea, fever, night sweats, and significant weight loss. Chest HRCT revealed centrilobular nodules, giving an initial impression of miliary tuberculosis. Therefore, he was started on an empirical, four-drug antituberculosis treatment regimen. Four weeks later, despite the tuberculosis treatment, he continued to have the same symptoms. We then performed transbronchial lung biopsy. Histopathological analysis of the biopsy sample revealed birefringent foreign body granuloma. A corroborative history of cocaine snorting, the presence of centrilobular nodules, and the foreign body-related histopathological findings led to a diagnosis of pulmonary foreign body granulomatosis. This report underscores the fact that pulmonary foreign body granulomatosis should be included in the differential diagnosis of clinical profiles resembling tuberculosis.
RESUMO Descrevemos o caso de um homem de 33 anos de idade, usuário crônico de cocaína em pó, que apresentava dispneia, febre, sudorese noturna e perda de peso significativa. A TCAR de tórax revelou nódulos centrolobulares, dando uma impressão inicial de tuberculose miliar. Por isso, o paciente passou a receber tratamento empírico com quatro tuberculostáticos. Quatro semanas depois, apesar do tratamento antituberculose, o paciente continuou a apresentar os mesmos sintomas. Foi então realizada a biópsia pulmonar transbrônquica. A análise histopatológica da amostra obtida revelou granuloma de corpo estranho birrefringente. A história de uso de cocaína por inalação, a presença de nódulos centrolobulares e os achados histopatológicos de corpos estranhos confirmaram o diagnóstico de granulomatose pulmonar de corpo estranho. Este relato destaca o fato de que a granulomatose pulmonar de corpo estranho deve ser incluída no diagnóstico diferencial de perfis clínicos que se assemelham a tuberculose.
Subject(s)
Humans , Male , Adult , Granuloma, Foreign-Body/etiology , Cocaine-Related Disorders/complications , Lung Diseases/etiology , Granuloma, Foreign-Body/diagnosis , Fatal Outcome , Lung Diseases/diagnosisABSTRACT
We report a patient with a wooden foreign body granuloma in the intervertebral disc space being symptomatic 17 years after a paraspinal penetrant trauma. According to the our result of the search for wooden foreign body granulomas, this is the first case suffered from a wooden foreign body granuloma in the intervertebral disc space that reported in the literature. In this report, we emphasized the importance of rigorous examination and follow up in paraspinal wooden penetrant traumas.
Subject(s)
Humans , Follow-Up Studies , Foreign Bodies , Granuloma , Granuloma, Foreign-Body , Intervertebral Disc , Spinal InjuriesABSTRACT
Foreign body granulomas can develop after the injection of various cosmetic filling materials into the facial area to flatten wrinkles. Clinically, reactive lesions are easily mistaken for soft-tissue neoplasms or cysts. This report presents a case of foreign body granuloma in a 52-year-old female patient complaining of a painless swelling in the nasolabial region. Both clinical and histological features are described, underscoring the diagnostic role of magnetic resonance imaging findings.
Subject(s)
Female , Humans , Middle Aged , Granuloma, Foreign-Body , Magnetic Resonance ImagingABSTRACT
Traumatic neuromas are rare benign tumors that are common after trauma or surgery and are usually accompanied by obvious symptoms of pain. Most reports show neuromas in the face, neck, and limbs, and the traumatic neuroma of the medial plantar nerve has rarely been reported. We encountered a traumatic neuroma of the medial plantar nerve after a deep laceration mimicking a foreign body granuloma. A small mass lesion was found around plantar aponeurosis with heterogeneous high signal intensity in the T2 fat suppression view and slightly enhanced intensity in the magnetic resonance imaging that suggested a foreign body granuloma. The lesion was diagnosed pathologically as a traumatic neuroma. A satisfactory clinical result was obtained after excision of the traumatic neuroma and burial of the proximal and distal stumps to the adjacent muscle at the secondary operation.
Subject(s)
Burial , Extremities , Foot , Foreign Bodies , Granuloma, Foreign-Body , Lacerations , Magnetic Resonance Imaging , Neck , Neuroma , Tibial NerveABSTRACT
SUMMARY Although the ingestion of foreign bodies is a common clinical problem, severe complications such as perforation are rare and occur in less than 1% of cases. Different types of foreign bodies and the various affected regions within the gastrointestinal tract make foreign body ingestion a complex entity, with a wide range of presentation requiring different diagnostic modalities. We report two cases of patients who underwent endoscopic ultrasound for evaluation of sub-epithelial lesions consisting of foreign body granulomas in the colon and rectum. Colorectal foreign body granuloma is a rare complication after accidental ingestion. Endoscopic ultrasound can be a useful diagnostic tool and can avoid the need for more invasive procedures.
RESUMO Embora a ingestão de corpos estranhos seja uma condição clínica frequente, complicações graves como perfuração são raras e ocorrem em menos de 1% dos casos. Tipos diferentes de corpos estranhos e as diversas regiões afetadas do trato gastrointestinal fazem da ingestão de corpos estranhos uma entidade complexa, com uma variada gama de apresentações, demandando várias modalidades diagnósticas. Nós reportamos dois casos de pacientes que foram submetidos à ultrassonografia endoscópica para avaliação de lesões subepiteliais, consistindo em granulomas de corpo estranho no cólon e no reto. Granulomas de corpo estranho colorretais são uma complicação rara após ingestão acidental. Ultrassonografia endoscópica pode ser uma ferramenta diagnóstica útil e pode evitar procedimentos mais invasivos.
Subject(s)
Humans , Male , Granuloma, Foreign-Body/diagnostic imaging , Colon/diagnostic imaging , Foreign Bodies/diagnostic imaging , Granuloma, Foreign-Body/etiology , Endosonography/methods , Foreign Bodies/complicationsABSTRACT
Schistosoma mansoni antigens in the early life alter homologous and heterologous immunity during postnatal infections. We evaluate the immunity to parasite antigens and ovalbumin (OA) in adult mice born/suckled by schistosomotic mothers. Newborns were divided into: born (BIM), suckled (SIM) or born/suckled (BSIM) in schistosomotic mothers, and animals from noninfected mothers (control). When adults, the mice were infected and compared the hepatic granuloma size and cellularity. Some animals were OA + adjuvant immunised. We evaluated hypersensitivity reactions (HR), antibodies levels (IgG1/IgG2a) anti-soluble egg antigen and anti-soluble worm antigen preparation, and anti-OA, cytokine production, and CD4+FoxP3+T-cells by splenocytes. Compared to control group, BIM mice showed a greater quantity of granulomas and collagen deposition, whereas SIM and BSIM presented smaller granulomas. BSIM group exhibited the lowest levels of anti-parasite antibodies. For anti-OA immunity, immediate HR was suppressed in all groups, with greater intensity in SIM mice accompanied of the remarkable level of basal CD4+FoxP3+T-cells. BIM and SIM groups produced less interleukin (IL)-4 and interferon (IFN)-g. In BSIM, there was higher production of IL-10 and IFN-g, but lower levels of IL-4 and CD4+FoxP3+T-cells. Thus, pregnancy in schistosomotic mothers intensified hepatic fibrosis, whereas breastfeeding diminished granulomas in descendants. Separately, pregnancy and breastfeeding could suppress heterologous immunity; however, when combined, the responses could be partially restored in infected descendants.
Subject(s)
Animals , Female , Male , Mice , Pregnancy , Animals, Suckling/immunology , Antibodies, Helminth/immunology , Granuloma, Foreign-Body/immunology , Immunity, Humoral/physiology , Liver Diseases, Parasitic/immunology , Schistosomiasis mansoni/immunology , Adjuvants, Immunologic , Animals, Newborn , Animals, Suckling/parasitology , /parasitology , Cercaria/immunology , Enzyme-Linked Immunosorbent Assay , Flow Cytometry , Forkhead Transcription Factors/blood , Granuloma, Foreign-Body/parasitology , Granuloma, Foreign-Body/pathology , Immunity, Heterologous/physiology , Immunoglobulin G/blood , Interferon-gamma/blood , /blood , /blood , Liver Cirrhosis/immunology , Liver Cirrhosis/parasitology , Liver Diseases, Parasitic/pathology , Mothers , Ovalbumin/immunology , Schistosoma mansoni/immunology , Spleen/immunology , Spleen/pathologyABSTRACT
Os autores apresentam o caso de uma paciente submetida 7 anos após aplicação de polimetilmetacrilato (PMMA) a um facelift com implante de prótese mentoniana, o qual evoluiu com granuloma por corpo estranho em região distante da aplicação do preenchimento. Após quase um ano de tratamento, a paciente evoluiu com resolução do caso.
The authors present the case of a patient who underwent a facelift with a chin implant 7 years after polymethylmethacrylate (PMMA) implantation, which evolved with foreign body granuloma in a region distant from the filling application. After nearly a year of treatment, the patient evolved with resolution of the granuloma.